WEST UNION - St. Marys jumped out to a 25-2 lead after the first quarter and never looked back in crushing Tyler Consolidated.
The Blue Devils will face Trinity, a 66-64 winner against Clay-Battelle, for the sectional crown Friday.
Audra Clark poured in 27 points and grabbed 15 rebounds for St. Marys (21-1), which shot 37 of 66 from the field.
Abby fetty added 17 points for the Blue Devils, while Kendra Walker scored 15.
Sophie Kinnard scored 13 points and Torrye Cline had 10 for the Silver Knights (9-13).