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Cleveland Indians' Carlos Santana throws out Chicago White Sox's James McCann at first base during the eighth inning of a baseball game, Tuesday, May 7, 2019, in Cleveland. The White Sox defeated the Indians 2-0. (AP Photo/Ron Schwane)

CLEVELAND (AP) — Lucas Giolito carried a shutout into the eighth inning and James McCann stayed with hot with an RBI single, leading the Chicago White Sox to a win over the light-hitting, light-scoring Cleveland Indians, 2-0.

Giolito (3-1) didn’t have to work hard against the Indians, who came in batting an AL-low .213 — 13 points lower than the next closest team, and 62 behind the league-leading Houston Astros.

The Indians wasted a strong outing by starter Jefry Rodriguez (0-2). Cleveland has been shut out twice in three games and scored just one run in the past 27 innings.

Giolito, who allowed just three hits, retired the leadoff hitter to start what became an eventful eighth.

The right-hander was lifted after 105 pitches for reliever Jace Fry, who got the second out before the Indians loaded the bases on a single, double and walk.

Phillies 11, Cardinals 1

ST. LOUIS (AP) — Bryce Harper hit a grand slam, his first with the Phillies, and Rhys Hoskins added four hits, including a homer, to spark Philadelphia to an 11-1 rout of the St. Louis Cardinals.

Harper’s homer capped a six-run second inning. Philadelphia took advantage of two errors and two walks as all six runs were unearned.

Aaron Nola (3-0) allowed three hits in six innings, giving up one run. He struck out seven.

Cubs 5, Marlins 2

CHICAGO (AP) — Kris Bryant hit a tiebreaking three-run homer with two out in the ninth inning, lifting the Chicago Cubs to a victory over the Miami Marlins.

With runners on the corners, Bryant drove a 1-2 pitch from Adam Conley (1-4) through a strong wind and into the bleachers in left-center for his third career game-ending homer.

Albert Almora Jr. also connected as the Cubs won for the eighth time in nine games. Steve Cishek (1-1) worked a scoreless ninth for the victory.

Brewers 6, Nationals 0

MILWAUKEE (AP) — Lorenzo Cain’s three-run double with two outs in the seventh inning broke a scoreless tie and the Milwaukee Brewers beat the Washington Nationals for their fifth straight win.

Nationals star Anthony Rendon had a rough and frustrating return to the lineup after missing 14 games because of a bruised left elbow caused when he was hit by a pitch. His first time up, he was plunked in the upper ribcage by a pitch from Adrian Houser, with the pitch barely missing Rendon’s left elbow.

Yankees 5, Mariners 4

NEW YORK (AP) — Cameron Maybin narrowly beat right fielder Jay Bruce’s throw home on DJ LeMahieu’s game-ending, ninth-inning hit, lifting the New York Yankees over the Seattle Mariners.

LeMahieu drove a single to right off Roenis Elias, and Maybin charged in from second and slid feet-first around a tag from catcher Omar Narv’ez. Plate umpire Dana DeMuth’s safe call was upheld on replay review.

Gio Urshela hit a tying two-run homer three batters earlier, a shot to center off Anthony Swarzak (2-2). That shot jolted a waterlogged Yankee Stadium crowd that had been jeering its own players amid sloppy play and missed chances in the later innings. New York stranded two runners in each of the sixth, seventh and eighth innings.

Red Sox 8, Orioles 5

BALTIMORE (AP) — Mitch Moreland hit a three-run homer and J.D. Martinez and Xander Bogaerts also connected to help the Boston Red Sox beat the Baltimore Orioles.

After having their run of six straight games with a long ball snapped by Baltimore one night earlier, the Red Sox scored their first six runs on homers and won for the seventh time in nine games.

Angels 5, Tigers 2

DETROIT (AP) — Shohei Ohtani went 0 for 4 with an RBI groundout and walked once in his season debut as the Los Angeles Angels beat the Detroit Tigers.

The Angels activated the AL Rookie of the Year from the injured list and looking very eager to make an impact, Ohtani swung so hard at times that his helmet flew off his head.

Ohtani took a called third strike in his first at-bat, grounded out to help Los Angeles take a 3-0 lead in the third, struck out on a breaking pitch, lined out to third and drew a base on balls.

The 24-year-old two-way player isn’t expected to pitch this year as he recovers from Tommy John surgery in October. But the Angels, who are under .500, are hoping he can provide a boost as their designated hitter.

Twins 3, Blue Jays 0

TORONTO (AP) — Jose Berrios allowed four hits in seven innings, Mitch Garver homered and the Minnesota Twins shut out the Toronto Blue Jays for the second straight night.

Berrios (6-1) won a career-best fifth consecutive start as the AL Central-leading Twins won for the eighth time in 11 games and moved a season-high 10 games over .500. The 24-year-old right-hander struck out five.

Royals 12, Astros 2

HOUSTON (AP) — Whit Merrifield and Ryan O’Hearn each hit a grand slam to lead the Kansas City Royals to a romp over the Houston Astros.

Danny Duffy (1-1) allowed six hits and two runs in 6 2/3 innings for his first win this season in his third start after missing the early part of the season with a shoulder injury.

Rays 6, Diamondbacks 3

ST. PETERSBURG, Fla. (AP) — Brandon Lowe homered on the first pitch in the bottom of the first, opener Ryne Stanek and five other relievers combined on a seven-hitter, and the Tampa Bay Rays moved to a season-high 11 games over .500 with a win over the Arizona Diamondbacks.

Lowe drove in his second run on a grounder during a three-run seventh as Tampa Bay improved to 9-1-2 in series play by taking the first two games of the three-game set.

After Stanek struck out four in two innings, winner Jalen Beeks (2-0) gave up one run and three hits in 3 1/3 innings.

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