Filler in Meds Is Not the Cause of Reader’s Symptoms
DEAR DR. ROACH: I have a question about excipients, something you discussed in a recent column about thyroid medication. Twice in my life, I took Celebrex for orthopedic pain. The episodes were about five years apart. Both times, I suffered severe liver dysfunction, turned yellow, lost weight and had dark urine and abnormal ALT, AST and bilirubin counts, etc. My doctor said the reaction was caused by the sulfonamide base, or “excipient,” in Celebrex, and not by the active ingredients. Is sulfonamide used as an excipient in many other drugs? Should I be wary of them as well? Is there ...