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PITTSBURGH (AP) -- Miguel Rojas hit a tying home run with two outs in the ninth inning and Garrett Cooper connected in the 10th as the Miami Marlins rallied for a 5-4 victory over the Pittsburgh Pirates on Tuesday night, ending their franchise-record 15-game road losing streak.
The Marlins were down to their final out when Rojas homered to center field off Felipe Vazquez, who had just his third blown save in 27 opportunities.
Cooper's home run, a 444-foot shot to left-center, came with one out off Parker Markel (0-1).
Adam Conley (2-7) got the last out of the ninth when Pablo Reyes was thrown out at home while trying to score from second base on Adam Frazier's infield single.
Jose Urena pitched a perfect 10th for his first save of the season and second of his career. He was Miami's opening day starter this year.
Pittsburgh had gone in front in the eighth as Jason Martin scored on Jarlin Garcia's wild pitch with two outs and the bases loaded.
Frazier led off the first inning with a home run, drove in three runs and had three of the Pirates' four hits. Pittsburgh lost for just the third time in 11 games.
Miami All-Star Sandy Alcantara remained winless since June 21, a span of 12 starts, as he allowed four runs and three hits in seven-plus innings with seven strikeouts and four walks.
Pirates rookie right-hander Mitch Keller left the game in the second inning when he sustained a bruised right wrist when struck by Cooper's line comebacker.
Considered the organization's top prospect coming into the season, Keller retired all five batters he faced in his eighth major league start.
Keller was struck flush on the outer part of the wrist. The Pirates said initial imaging revealed only a bruise.
Frazier's two-run single to right field in the bottom of the fifth tied the game at 3-3. The Marlins had pulled ahead in the top of the inning on Cooper's RBI double to deep center field.
After Frazier staked the Pirates to a quick lead, the Marlins moved ahead 2-1 in the third inning as a throwing error by third baseman Colin Moran on Cooper's two-out grounder allowed two runs to score.
INSTANT OFFENSE
Frazier's leadoff blast marked the fourth time in five games the Pirates started a game with a home run. The second baseman had one and SS Kevin Newman hit two during a four-game sweep last weekend at Colorado.
OH BROTHER
LHP Brian Moran was called up by the Marlins from Class AAA New Orleans along with C Tyler Heineman and OF Magneuris Sierra. Moran is the older brother of Colin Moran and reached the major leagues for the first time after spending 10 years in the minors.
The Morans are nephews of longtime major leaguer B.J. Surhoff.
The Marlins designated C Wilkin Castillo for assignment and transferred 3B/OF Brian Anderson (fractured right hand) to the 60-day injured list from the 10-day IL to open spots on the 40-man roster.
NEW OLD PIRATE
LHP Wei-Chung Wang was added to the Pirates' active roster three days after being claimed off waivers from the Oakland Athletics. The Pirates signed Wang from Taiwan as an amateur international free agent in 2011 then lost him two years later to the Milwaukee Brewers in the Rule 5 Draft
Martin, an outfielder, was called up from Triple-A Indianapolis as were RHP Yacksel Rios, C Steven Barron and INF Cole Tucker.
PHILLIES 6, REDS 2
CINCINNATI (AP) -- Bryce Harper drove in his 100th run with a single, J.T. Realmuto had a pair of hits and a sacrifice fly, and the Philadelphia Phillies won their third in a row over the Cincinnati Reds.
YANKEES 10, RANGERS 1
NEW YORK (AP) -- James Paxton pitched one-hit ball for seven shutout innings, striking out 12 and winning his seventh straight start as New York beat Texas.
BRAVES 7, BLUE JAYS 2
ATLANTA (AP) -- Josh Donaldson doubled and drove in three runs, Mike Foltynewicz pitched five scoreless innings, and streaking Atlanta won its sixth straight game.
WHITE SOX 6, INDIANS 5
CLEVELAND (AP) -- Carlos Carrasco received a standing ovation in his first appearance at Progressive Field since being diagnosed with leukemia, but gave up home runs to James McCann and Eloy Jimenez in the eighth inning that lifted Chicago over Cleveland.
BREWERS 4, ASTROS 2
MILWAUKEE (AP) -- Zack Greinke lost his first game since joining Houston, giving up a three-run homer to Eric Thames as Milwaukee earned a split of the interleague series.
Greinke (4-1) stumbled for the first time in six starts since being traded from Arizona on July 31st. He allowed four runs on eight hits over six innings. He came in 4-0 in his five previous starts.
CARDINALS 1, GIANTS 0
ST. LOUIS (AP) -- Jack Flaherty pitched one-hit ball over eight innings, Marcell Ozuna homered and St. Louis-- with a fluky foul ball-turned-base hit -- beat San Francisco.
NATIONALS 11, METS 10
WASHINGTON (AP) -- Kurt Suzuki capped the largest ninth-inning comeback in Nationals history with a game-ending, three-run homer, helping Washington score seven runs in its final at-bat to beat New York.
ORIOLES 4, RAYS 2, 1ST GAME
RAYS 2, ORIOLES 0, 2ND GAME
ST. PETERSBURG, Fla. (AP) -- Austin Meadows homered, seven relievers combined on a five-hitter and playoff-contending Tampa Bay blanked Baltimore to split a doubleheader.
TWINS 6, RED SOX 5
BOSTON (AP) -- Nelson Cruz and Miguel Sano connected in the fifth inning to pad Minnesota's record home run total in a victory over Boston.
CUBS 6, MARINERS 1
CHICAGO (AP) -- Nicholas Castellanos homered and drove in four runs, and the Chicago Cubs celebrated the return of Willson Contreras and Ben Zobrist by topping the Seattle Mariners.
Jon Lester (12-9) escaped three bases-loaded jams while working six innings in his second straight win, helping Chicago stay three games back of NL Central-leading St. Louis. The Cubs also remained 2¢ games ahead of Philadelphia for the second NL wild card.
Daniel Vogelbach's pinch-hit RBI single in the eighth accounted for Seattle's only run in its fourth loss in five games.